Sustained Release Matrix Tablet of Tramadol HCl: Box-Behnken Design For Optimization of Formulation Variables of Tramadol HCl Sustained Release Matrix Tablet

Sustained Release Matrix Tablet of Tramadol HCl: Box-Behnken

To develop sustained release matrix tablet of Tramadol HCl that deliver drug for 24 hr and to be taken once in a day. Drug having high solubility and relatively shorter half-life suggests its suitability for an extended formulation. If it is formulated by conventional tablets, it will require multiple daily administrations which ultimately results into inconveniency to the patients and possibility of reduced compliance with prescribed therapy. Also fluctuation in plasma drug concentration leads to exaggerated side effects, this all limitations can be minimized by adopting extended release formulation. To reduce the frequency of administration and to improve the patient compliance, Once in a day sustained release formulation is desirable. It describes the influence of the concentration of HPMC K4M, HPMC K15M and HPMC K100M on Tramadol HCl sustained release formulations using box-behnken design.These Polymers were selected as an independent variables. Drug release after 8 hr, 12 hr and 16 hr were selected as a dependent variables. Optimized formulation found by similarity and dissimilarity factor follow zero order kinetic with non-fickian diffusion as a drug release mechanism.

  • ASIN: 3659159840

PetAlive AmazaPet Tablets - A Homeopathic Remedy for Easier Breathing, Improved Respiratory Function and Healthy Lungs

PetAlive AmazaPet Tablets - A Homeopathic Remedy for

Few things are more distressing than seeing your pet struggle to breathe through an acute coughing or wheezing episode. Everyday activities such as playing fetch outside could suddenly be too much for a dog; certain brands of litter may cause a cat to cough uncontrollably. Other symptoms of poor respiratory functioning can range from loss of appetite or weight and shortness of breath, all of which can lessen your pet's quality of life. AmazaPet is a powerful homeopathic formulation for addressing poor respiratory functioning and promoting healthy lungs. Using a unique, proprietary blend of highly diluted and scientifically selected natural substances, AmazaPet offers an effective and safe choice for easier breathing, healthy respiratory functioning, and comfort. Symptoms of respiratory issues can present as nothing more than a dry, hacking cough, possibly progressing to wheezing sounds becoming more obvious when your pet exhales. You may notice shallow, rapid, labored breathing with marked movement of the abdomen. Your pet is trying to breathe in more air. Cats, for example, tend to extend their heads, possibly even adopting a praying position with elbows extended away from the chest. Coughing and wheezing can be triggered by allergens and stress. Some common allergens can includ...

  • Brand: PetAlive
  • ASIN: B002X95YSE
  • UPC: 810845012126

Dog Hip and Joint Support; All Natural Homeopathic Supplement and Anti-Inflammatory Helps Relieve Chronic Arthritis Pain and Improve Mobility with No Side-Effects

Dog Hip and Joint Support; All Natural Homeopathic

Keep your dog bouncing, running, and having fun long into their older years with an all-natural, homeopathic hip and joint supplement from Petsability. There's nothing more fun than coming home after a long day and spending the time running around the yard or playing fetch with your dog. But when they're struggling with chronic hip and joint pain, it can really slow them down and keep them from living the healthy, active lifestyle they deserve. We developed Petsability Hip and Joint for Dogs as a smarter, homeopathic way to help relieve those aches and pains and restore vital mobility. A natural formulation of essential plant minerals, our small tablets work quickly to keep your pet healthy and energetic as they age, so you can both create a lasting relationship built on playful fun and excitement. Product Details: Homeopathic Hip and Joint Supplement and Arthritis Pain Relief Medicine for Dogs Quick Dissolve Tablets Gentle on Sensitive Stomachs Safe to Use with Other Treats, Supplements or Treatments No Artificial Flavors, Additives, or Preservatives Safe for all canine breeds: from Puppies, to Small and Large Adults, and Older Dogs Volume: 25 grams - a one to two month supply of pellets Made in an FDA-Registered Facility Guaranteed Satisfaction Click 'Add to Cart...

  • Brand: Petsability
  • ASIN: B07H828XBP
  • UPC: 628250142211

New Chapter Joint Supplement + Herbal Pain Relief - Zyflamend Whole Body for Healthy Inflammation Response - 120 ct

New Chapter Joint Supplement + Herbal Pain Relief

Is your joint supplement relieving pain? Zyflamend works on pain right where it starts—keeping in check the inflammation response that impacts joint comfort and mobility.*+ Zyflamend is an excellent herbal complement to glucosamine, which is a cartilage supplement that does not address inflammation. New Chapter’s #1-selling herbal blend gives you 4-in-1 complete benefits: supporting healthy inflammation response, mobility, flexibility, and overall joint support and comfort.* Expertly formulated with 10 synergistic herbs including potent Ginger, Turmeric, and Green Tea.*+ (+ with Ginger for occasional pain relief after exercise)

  • Brand: New Chapter
  • ASIN: B014GSWJI2
  • UPC: 727783900753

Penetrex Pain Relief Therapy - Large (4 Oz.) Size :: The Preferred Value for Daily Users & Health Care Professionals

Penetrex Pain Relief Therapy - Large (4 Oz.)

Penetrex absorbs Quickly & Easily into the Back, Neck, Knee, Hand, Foot, Shoulder, Elbow, Wrist, Hip, Shin, Calf, and more. ► 100% Satisfaction Guaranteed ✓ ► No Embarrassing Odor ✓ ► No Animal Testing ✓ ► U.S.A. Made ✓ Penetrex is Quick, Strong, & Long-Lasting. ► Vanishing Scent ✓ ► Non-Staining ✓ ► Non-Greasy ✓ ► Paraben-Free ✓ Formulated to Address the Root of the Problem, Underlying Inflammation. ► No Burning or Freezing ✓ ► No Artificial Temperature Sensations ✓ ► 8+ Years of Research & Development ✓ ► Produced in an F.D.A. Certified Laboratory ✓ Intensive Concentrate Requires Fewer Applications. ► Drug-free ✓ ► Steroid-free ✓ ► No Side-Effects ✓ ► Over 2 Million Jars Shipped ✓ A Breakthrough Delivery System Carries These Clinically Proven Ingredients: ► Arnica ✓ ► Choline ✓ ► Glucosamine ✓ ► MSM (DMSO2) ✓ ► Boswellia Serrata ✓ ► Cetyl Myristoleate ✓ ► Vitamin B6 (Pyridoxine) ✓ ► ...and More! Since 2009, This Alternative Approach to Topical Pain Management Has Established an Unmatched Track Record of Delivering Breakthrough Results to Over 2 Million Sufferers Worldwide. Just 2 or 3 Years Ago Penetrex Was Truly a Best Kept Secret. The WORLD Now Knows About This Amazing For...

  • Brand: Penetrex
  • ASIN: B00DI7U88G
  • UPC: 748252272218

Cellfood Sam-e Liquid Formula +, 1 oz. - Superior Absorption, Helps Support Healthy Mood Levels, Joint and Liver Health - Gluten Free, GMO Free

Cellfood Sam-e Liquid Formula +, 1 oz. -

Cellfood SAM-e is a breakthrough in modern nutritional chemistry- a liquid SAM-e formulation that combines the clinically-proven benefits of S-adenosyl methionine with Cellfood's nutritional value and unparalled delivery system. The result is a unique nutritional supplement providing benefits for supporting mood and emotional well-being, joint mobility and liver health.

  • Brand: Cellfood
  • ASIN: B009HWF6DI
  • UPC: 639767744034

Dr Reckeweg Strophanthus Q (Mother Tincture) 20ml

Dr Reckeweg Strophanthus Q (Mother Tincture)

Dr Reckeweg Strophanthus Q (Mother Tincture) 20ml ...

  • Brand: Dr. Reckeweg
  • ASIN: B00SQF02HC

Nature's Way Umcka® FastActives® Cold Relief Shortens Duration, Cherry Flavored, Rapidly Melts In Your Mouth, 10 Powder Packets

Nature's Way Umcka® FastActives® Cold Relief Shortens Duration,

Shortens duration and reduces severity of symptoms associated with the common cold and throat/sinus/bronchial imfections: congestion, cough, headache, hoarseness, minor aches, Sore Throat and helps loosen phlegm (mucus) to make coughs more productive.

  • Brand: Nature's Way
  • ASIN: B001JHBBA6
  • UPC: 033674153475

AMRITA Aromatherapy: Muscle Tension and Cold Relief Massage & Body Oil With Pure and Therapeutic Grade Essential Oils of Eucalyptus Radiata, Lemongrass & Birch - Size: 240ML

AMRITA Aromatherapy: Muscle Tension and Cold Relief Massage

Muscle Tension & Cold Relief Body Oil: A warming, analgesic blend of Amrita's fine body oil base with luxurious essential oils. Birch helps to reduce pain, Eucalyptus Radiata increases blood flow to the tissues, and Lemongrass warms and relaxes tense muscles. This body oil will help relieve you of everyday stress. Ideal during the cold and flu season.

  • Brand: Amrita Aromatherapy
  • ASIN: B0755SWKN9

Ancient Minerals Magnesium Gel Ultra with OptiMSM and Aloe Vera - Topical Magnesium Gel Formula with MSM Best Used for Dermal Skin Absorption and Massage Therapy (8oz)

Ancient Minerals Magnesium Gel Ultra with OptiMSM and

Ancient Minerals Magnesium Gel is a uniqued gelled formulation of our high purity ancient magnesium chloride and biologically active organic aloe vera extract in therapeutic amounts. This professional strength magnesium gel formulation was developed for sustained release of magnesium chloride and aloe vera polysaccharides by the skin. Ancient Minerals Magnesium Gel stays hydrated when applied, and is designed not to be fully absorbed.

  • UPC: 853956003584
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